Program: IgY-112 Stage: Discovery IgY for Celiac disease contain polyclonal IgY antibodies that block the interaction of hypersensitive or excessive mucosal immune responses with microbial and protein components that are associated with celiac disease pathogenesis. We are researching the effectiveness of an oral therapeutic using a capsule-based format to deliver the antibodies directly [...]
Program: ASF Stage: Discovery African Swine Fever (ASF) is lethal hemorrhagic disease in domestic and wild pigs. It is caused by ASF Virus (ASFV). Polyclonal antibodies IgY are designed to target entire virus particles, the viral proteins expressed upon natural infection and host factors that are involved in pathogenesis of ASF. ASFV-IgY could [...]
Program: IGY-110 Stage: Preclinical IGY-110 is an IgY polyclonal antibody targeting the spike proteins of the coronavirus directly via intranasal delivery to the key site of coronavirus entry and infection. Enteric-coated capsules will also be used to help reduce virus activity in the gastrointestinal tract. The intranasal delivery approach is supported by a recent [...]
Program: IgY-102 Stage: Discovery Universal influenza IgY nasal spray contains polyclonal antibodies IgY that neutralize a broad spectrum of influenza virus strains including those that cause potential pandemics. The concept is based on the study published in PloS ONE, DOI: 10.1371/journal.pone.0010152 Please contact us to learn more about IGY-102 or to explore partnership [...]
Applications Biologics and Pharmaceuticals Source Chicken eggs from immunized hens targeting specific pathogen(s) Health Outcomes Immune enhancement and disease mitigation IgY antibodies created to target specific antigens are intended to have a localized, highly target-specific, predictable, and efficient antigen-antibody interaction. Antigens can be complex antigens from viruses, bacteria or parasites or single antigens [...]